The Metabolism and Transport Drug Interaction Database (DIDB ®) and the Pharmacogenetics Database (e-PKGene ®) are part of a knowledge base (“DIDB Platform”) designed for scientists and clinicians working in the field of drug development, drug disposition and drug-drug interactions (DDIs). Improving long-term subcutaneous drug delivery by regulating material-bioenvironment interaction ☆ Even though herbal supplements may be from plant or herb sources, the active ingredients can still be potent chemicals. Because of this, herbal supplements can have drug interactions, even with each other or with food or alcohol. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine. Possible illicit drug use should be considered when prescribing medicines that have the potential to interact adversely. If you're taking a medication, either prescription or non-prescription, you're at risk of a drug interaction. Each drug could interact with other medications, vitamins, supplements and even foods.